The Positive and Negative Outcome of Morphine and Disulfiram Subacute Co-Administration in Rats in the Absence of Ethanol Challenge

Recently, a well-known anti-alcohol agent, disulfiram (DSF), has gain much interest, as it was found to be effective in the treatment of copyright abusers, thus also giving hope for patients addicted to opioids and other illicit drugs.Therefore, this study was aimed to investigate the possible outcome that might occur within the subacute co-adminis

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Electrophiles against (Skin) Diseases: More Than Nrf2

The skin represents an indispensable barrier between the organism and the environment and is the first line of defense against exogenous insults.The transcription factor here NRF2 is a central regulator of cytoprotection and stress resistance.NRF2 is activated in response to oxidative stress by reactive oxygen species (ROS) and electrophiles.These

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Fostering holistic natural-risk resilience in spatial planning

Natural disasters cause destruction of (land/urban)scape values and cultural heritage, social and cultural ties, and have direct impact on spatial resources that appeal to spatial planning from a redken shades eq 07m driftwood perspective of enhancing present resilience and reducing future risks.The research aim is to build a knowledge framework on

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